Endocrine Abstracts

Hyponatraemia is the most frequent electrolyte disorder encountered in hospitalized patients. Hyponatraemia causes a wide variety of neurological signs and symptoms, depending on the rate and degree of serum sodium drop. The negative effects of low extracellular sodium concentrations ((Na+)) on neuronal cells are known to be due to the entry of fluids into the cells, as a consequence of reduced plasma osmolality. To date, it has not been investigated whether low (Na+) ...

Metabolic pathologies mainly originate from dysfunctions of the white adipose tissue (AT). Functional differences in AT and their impact on metabolism seem associated with the fat depot regional distribution, in particular the subcutaneous (SAT) and visceral (VAT) pads. Human adult adipose stem cell (ASC) populations have recently been characterized from SAT and VAT. In this study, using human ASC cultures obtained from paired biopsies of abdominal SAT, S-ASC, and VAT, V-ASC, ...